Antigen presenting cells or APCs - This lecture explains about the properties of Professional antigen presenting cells such as macrophage, dendritic cells and B cells. It also explains the importance of antigen presenting cells or APC to engulf a pathogen through phagocytosis and then presenting it to the whole immune system so that cell mediated and humoral immune response can build up. Mature, naive B- and T cells, as well as precursors of APC (antigen presenting cells, including monocytes/macrophages and dendritic cells) from the bone marrow emigrate from the central lymphatic organs. Lymphocytes travel mainly via the bloodstream. APC leave the bloodstream to widely roam tissues. Eventually, all types of cells meet again at the peripheral lymphatic organs: lymph nodes, GALT/Peyer plaques and tonsils, BALT and spleen.Lymph nodes seem static in the microscope, but should better be compared to the transit area of a big international airport, with oodles of cells arriving and leaving all the time. Lymph nodes have several inlets and an outlet. Afferent lymphatic vessels reaching the most peripheral lymph nodes transport the interstitial fluid filtrated from blood capillaries. With the lymph flow, dendritic cells loaded with ingested material drift to the lymph nodes, e. g., Langerhans cells from the skin. In case of an infection, lymph flow increases dramatically, carrying with it pathogens and their antigenic molecules, outside and inside of activated macrophages and dendritic cells. Thus, a lymph node is a local command center with continuous real-time information on the antigenic situation in the periphery. From the blood, lymphocytes constantly enter the lymph node via specialized high endothelial venules. B cells migrate to areas near the cortex, and, if activated, form follicles with germinal centers. There, specialized "follicular dendritic cells" immobilize immune complexes with their Fc- and complement receptors, so that the antigens are "visible" to the proliferating B cells. T cells wander to adjacent paracortical areas. Some activated B cells that already have differentiated to plasma cells, and more macrophages,sitinthe lymphnode'smedulla.Eachlymphnode hasanefferentvessel connecting to the next lymph node and, eventually, via the thoracic duct to the blood.(Caution: "dendritic cells" and "follicular dendritic cells" are completely different cell types that obtained similar names (dendritic = tree-like) because of their morphological appearance. Dendritic cells are specialized APC ingesting antigen in the periphery and presenting processed antigen on MHCII to T cells. Follicular dendritic cells sit in germinal centers anduse complement receptors and Fc receptors to fix antigen-containing immune complexes on their outer surface for B cells to see.)For more information, log on to-Shomu's Biology DVD set here-the study materials here-Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-storeShomu’s Biology assignment services – www.shomusbiology.com/assignment -helpJoin Online coaching for CSIR NET exam – www.shomusbiology.com/net-coachingWe are social. Find us on different sites here-Our Website – www.shomusbiology.comFacebook page- - www.slideshare.net/shomusbiologyGoogle plus- - you for watching the lecture on Antigen presenting cells.
Instant Karma & Police Justice #1
A 1080 HD version is also available at: This SD version was uploaded for those having trouble loading HD videos in Google ChromeThe extended remaster of the song "Stayin' Alive" by The Bee Gees with footage from Saturday Night Fever.The video editing was done using Sony Vegas 12. The extended editing of "Stayin' Alive" was done using Adobe Audition Cs6.0, adding very little in the way of the remastered sound.Thanks for watching. Enjoy :)
How to Prevent Heart Disease. About 610,000 people die from heart disease each year in the U.S. alone. There are tons of factors that can cause a person to develop heart problems, but most of them come down to poor lifestyle choices. Your body gives you warning signs early on so that you can catch an illness in its early stages or even prevent it altogether and save your life. Here are 10 of the most common red flags that indicate bad heart health.#heartproblems #healthyheart #bodysignsA cough that won't quit 1:38A persistent cough can be a symptom of all kinds of health issues, and cardiovascular disease is one of them. For instance, a chronic cough that produces a pinkish bloody liquid is very common in people with heart failure. Despite what it sounds like, heart failure doesn't mean that the heart completely stops beating. It just means that a person’s heart isn’t pumping blood as well as it should be. As a result, the body doesn't get enough oxygen since it’s carried to all the tissues by the blood.Nausea and loss of appetite 3:07A lot of heart disease patients show a lack of appetite, nausea, or both, even if they've had just a couple bites of food. The reason for that is built-up fluid around the liver and intestines that interferes with proper digestion. These symptoms are usually accompanied by abdominal pain, upset stomach, or feeling bloated. In fact, abdominal cramps that come and go in short spurts are extremely common right before a heart attack.Your skin becomes paler or takes on a bluish tint 5:28Being naturally pale doesn’t necessarily mean you have a heart condition. But sudden paleness can be a result of reduced blood flow due to a heart that’s not pumping blood as effectively as it should be. Shock, which can be caused by any condition that prevents the blood in your body from circulating properly, is the main reason why people who are suffering from a heart attack or heart failure turn pale all of a sudden.Chronic or sudden fatigue 7:02Fatigue can be one of the main symptoms indicating an impending heart attack. Women are more likely to experience heart-related fatigue than men, with 70% of female heart attack patients reporting that they’d felt extremely tired before their episode. Physical or mental activity isn't the reason for such exhaustion, and it increases by the end of the day if it’s due to a failing heart. It’s really hard for this symptom to go unnoticed. Sometimes it's exhausting just to perform even the simplest tasks, like making the bed or taking a shower.Music: The 126ers-Darkness of My SunDensity & Time-City of JewelsPain that spreads to the arm 1:019. A cough that won't quit 1:388. Swollen legs, ankles, and feet 2:257. Nausea and loss of appetite 3:076. Extreme levels of anxiety 3:475. Lightheadedness or fainting 4:264. Your skin becomes paler or takes on a bluish tint 5:283. Skin rashes or unusual spots 6:202. Chronic or sudden fatigue 7:021. Increased perspiration 7:45SUMMARY-If their heart isn’t working properly, a lot of men feel pain in their left arm, while women experience the same pain in either or both arms.-A persistent cough can be a symptom of all kinds of health issues, and cardiovascular disease is one of them.-When your heart isn’t pumping enough blood through the body, fluid from your blood vessels leaks into surrounding tissues. Your lower extremities are the most affected simply due to gravity.-A lot of heart disease patients show a lack of appetite, nausea, or both, even if they've had just a couple bites of food.-People who suffer from extreme anxiety from a very early age or most of their life are more prone to developing coronary heart disease.-Feeling lightheaded and experiencing temporary loss of consciousness, also known in the scientific community as “syncope”, is super common among heart patients.-Sudden paleness can be a result of reduced blood flow due to a heart that’s not pumping blood as effectively as it should be.-People with eczema were found to have a 48% chance of suffering from high blood pressure and a 29% possibility of having high cholesterol.-Sometimes it's exhausting just to perform even the simplest tasks, like making the bed or taking a shower before a heart attack. -People experience flu-like symptoms, have clammy skin, and sweat regardless of the air temperature or physical exertion.Subscribe to Bright Side : Social Media:Facebook: Crafts Youtube: more videos and articles visit:
los mas locos y lo mejorcito del humor cubano ..que queda en la isla
Holoooooou!! Bienvenidos a mi canal y chan chan chan... Jugamos ADIVINA QUIÉN con el Boss, FRANCO ESCAMILLA! Pero no es cualquier Adivina Quién, no... no, es la versión DIABLO SQUAD!! Qué preguntas hubieras hecho tú? Redes SocialesTwitter: MARTES Y JUEVES de 3 a 5 de la tarde está el programa #Pachequeando en #LaRadioSquad ¡Escúchalo! Recuerda descargar la aplicación oficial: Para iOS: Google Play: Página:
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CEC 09: Life Sciences Managed By UGC/CEC
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"She made us feel like we were a part of something special.. we were"Watch in HD!Can't believe it's really over. I'm definitely going to keep making pll videos though as well as others. Next is emison! ►Show - pretty little liars►Song - - sunnyvids►Program - Sony Vegas
Նոյեմբերի 24-ին Շանթ հեռուստատեսության եթերում կայացավ Հումորի լիգայի 1/4 եզրափակիչը, որտեղ մասնակցում էր Trio Studio-ն ներկայացնող ՙՙՈւրբաթ 13՚՚ թիմը: Շնորհավորում ենք մեր թիմին 1/2 եզրափակիչ փուլ անցնելու կապակցությամբ:
TOP 10 BEST Got Talent auditions EVER!I choose these songs on my personal point of view and it can be different from whatyou might have selected. So don't become Grumpy :P Thanks!Do let me know which one is better in your point of view.Enjoy! :)Alice Fredenham - My Funny Valentine - Britains Got Talent-2013 (00:00-08:10)Kevin Skinner -If Tomorrow Never Comes -America's Got Talent 2013(08:11-14:00)Calum Scott - Dancing on my own - Britains Got Talent 2015(14:01-18:37)David Fenley - Too Close - Americas Got Talent 2013(18:39-23:43)Michael Collings - Fast car - Britain's Got Talent 2011(23:45-29:15)Owen Campbell - Sunshine road -Australia's Got Talent 2012(29:16-36:43)Ryan O'Shaughnessy - No Name - Britains Got Talent 2012(36:44-43:55)Isaac Waddington - Always A Woman - Britain's Got Talent 2015 (43:56-46:24)Sam Kelly- Make You Feel My Love - Britains Got Talent 2012(46:25-53:57)- Britain got talent -America Got Talent -Australia Got Talent
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►►Subscribe to my main channel: my Facebook page: me on Twitter: after the events of the base game, Geralt is offered a contract by Duchess Anna Henrietta, the ruler of Toussaint, a vassal duchy under the Nilfgaardian Empire famous for its vineyards and wine exports. Two knights of Toussaint had been murdered in strange circumstances, and Geralt is tasked with finding and killing the monster responsible.Upon his arrival in Toussaint, Geralt investigates the murder of a third knight. With the help of Henrietta and Captain Damien de la Tour, the knight heading the investigations, Geralt discovers clues that suggests the knights were killed for violating the five virtues that all knights of Toussaint sworn by, and that a fourth knight may be in danger. Geralt and the duchess race to find the fourth knight, and Geralt arrives just in time to see the Beast killing the fourth knight, who had traveled with him to Toussaint. Geralt gives chase to the Beast, eventually cornering and battling him in a warehouse. Before either can kill the other, Regis, a higher vampire and friend of Geralt, intervenes and convinces the Beast to leave. Regis, who Geralt believed to be long dead from their past incursion, explained that the Beast is another higher vampire named Dettlaff. Regis was revived by Dettlaff after his supposed execution, resulting in the fact that Regis is bonded to Dettlaff by blood according to their vampiric code.----------Tracklist:----------01. Tavern (00:00)02. Blood And Wine (02:52)03. Mystery (05:49)04. Ambient (07:54)05. I Cannot Let You Leave (09:52)06. Fairy Tale (11:46)07. What Lies Unseen (Alt ver) (14:03)08. Track 08 (16:56)09. The Musty Scent of Fresh Pâté (19:15)10. Dialogue Theme (21:55)11. Tesham Mutna (24:03)12. Beauclair Castle (26:07)13. On the Champs-Désolés (28:11)14. Exploring The City (30:15)15. Minors (32:42)16. Beauclair (35:23)17. Vivienne (38:07)18. Diva (40:07)19. Suspense (42:16)20. Searching For Cecilia Bellant (44:29)21. Wine Wars (47:15)22. Beyond Hill And Dale... (49:28)23. Dialogue (Alt) (52:33)24. Detalff Destroyed (54:48)25. Explore (56:54)26. Investigation (59:02)27. Guillaume Versus The Shaelmaar (01:02:09)28. The Moon Over Mount Gorgon (01:04:04)29. Meadows (01:06:12)30. Living World (01:08:19)31. Dun Tynne Battle (01:10:26)32. Fanfares And Flowers (01:12:25)33. Gwent (01:15:43)34. Blood Run (01:18:46)35. Track 35 (01:21:04)36. Tavern (Alt) (01:24:32)37. The Banks Of The Sansretour (01:27:05)▪ SEE YOU IN THE NEXT ONE, STAY AWESOME! (•̀ᴗ•́)و ̑̑ ▪#######witcher musicwitcher 3 musicwitcher 3 ostwitcher 3 soundtrackwitcher 3 themewitcher 3 gameplaywitcher 3 relaxingwitcher 3 ambiance
This video “Recognition of Antigens: Receptors & Antibodies” is part of the Lecturio course “Lymphocyte Development” ► WATCH the complete course on LEARN ABOUT:- Recognition of antigens by the immune system- Receptors-PRR- Major histocompatibility complex- T-Cell receptor- Antibody► THE PROF: Peter Delves, Professor Emeritus of Immunology and former Vice Dean (Education) of the Faculty of Medical Sciences at University College London, is not only editor of two encyclopedias but also author of several textbooks and laboratory manuals. His special interest lies in improving an understanding of immunology through both web-based education and face-to-face interaction.► LECTURIO is your single-point resource for medical school:Study for your classes, USMLE Step 1, USMLE Step 2, MCAT or MBBS with video lectures by world-class professors, recall & USMLE-style questions and textbook articles. Create your free account now: INSTALL our free Lecturio appiTunes Store: Store: READ TEXTBOOK ARTICLES related to this video: Lymphocyte Development — B- and T-Cell DevelopmentSUBSCRIBE to our YouTube channel: WATCH MORE ON YOUTUBE: LET’S CONNECT:• Facebook: Instagram: Twitter:
These are some of my favourite art images. I've set them to Dvorak's Humoresque performed by Yo Yo Ma And Itzhak Perlman. These images include Andy Warhol, Sydney Pollock, Paul Klee, and Salvador Dali. Enjoy! Thank You For Your Comments.
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MHC- Tightly linked complex of genes encoding for cell surface molecules that are required for antigen presentation and rapid graft rejection.General organization and inheritance of MHCHistocompatibility antigens- Rejection of foreign tissues is a result of an immune response to cell surface molecules. This concept is known as histocompatibility antigens.MHC ENCODES THREE MAJOR CLASSES OF MOLECULESThe MHC complex is a tight collection of genes.The MHC is referred to as the HLA complex (located on chromosome 6) in humans and H2 complex (chromosome 17 ) in miceSTRUCTURE OF MHC CLASS I• Class I MHC molecules contain a 45kDa α chain (transmembrane glycoprotein encoded by ABC region of HLA complex) and a 12kDa β2 microglobulin molecule.• α chain contains 3 external domains (α1, α2 and α3), each contain approx. 90 amino acids• α chain contains a transmemebrane domain of approx. 25 hydrophobic amino acids followed by a small stretch of charged (hydrophilic) amino acids.• It also contains a cytoplasmic anchor segment of 30 amino acids• α1 and α2 interact to form 8 antiparallel β strands spanned by 2 α helices. This forms a deep groove or cleft of approx. 25Å X 10 Å X 11 Å with α helices as sides and β strands as the bottom. This peptide binding cleft is located on the top surface of the MHC molecule.• It can bind a peptide of 8-10 amino acids• α 3 and β2 are organized into 2β pleated sheets formed by antiparallel β strands.• α 3 is highly conserved and contains a sequence that interacts with CD8 molecules of Tc cells• β2 interacts with α 3 and also with α1 and α2. Interaction of β2 is important for a fully folded conformation.Assembly of Class I molecules• β2 microglobulin interact with α3 chain and helps the folding of α chain.• This structure is stabilized by binding of appropriate peptide to form naïve Class I structure. • This assembly is transported to the cell surface.• α 3 and β2 association is important for expression of Class I molecules on cell surface. If no interaction between them,then no active MHC.STRUCTURE OF MHC CLASS II• Class II molecules contain a 33kDa αchain (90 amino acids) and a 28kDa βchain (25 amino acids) which are associated by non covalent interactions.• They are membrane bound glycoproteins with external domain, transmemebrane domain and a cytoplasmic anchor segment.• There are two external domains: α1 and α2 domain, β1 and β2 domain.• Peptide binding cleft structure is similar to that in Class I MHC molecules, however class II molecules forms an open pocket instead of a closed pocket (due to lack of conserved residues that bond the terminal residues of short peptides).
Here are 5 critical nutrients to get started with on your journey to prevent and/or heal chronic inflammation and autoimmune disease.For more information read this article:Charge:Glutathione: D3/K2:30:100:Assist:Liver Oil:CRP:
Art Tatum (p), Everett Barksdale (g), & Slam Stewart (b).From the album, "Complete Capitol Recordings", Capitol.
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Official Taylor Trumpet artist by Marc-Antoine CharpentierFrom the Ancient English Cathedral of Norwich with David Dunnett on Organwww.johncoulton.comwww.taylortrumpets.com
Join WQXR for a very special night of live music and conversation as the “hottest artist on the classical music planet” (The New York Times) returns to The Greene Space.Lang Lang opens up about the inspiration behind his much-anticipated new solo project, Piano Book, his first studio album in three years. He’ll also discuss the ambitious education projects he is overseeing through his Foundation, and the personal journey that has brought him this far.Alongside intimate performances of some of the best-loved piano music of all time, Lang Lang will be in conversation with WQXR’s Creative Director, Clemency Burton-Hill.
La segunda parte de Contagiocidio.
The Duke of Wellington arrives to challenge the Prince to a duel, unaware that he and Blackadder have exchanged places. Subscribe to the BBC Studios channel: Studios Channel: is a channel from BBC Studios who help fund new BBC programmes..Subscribe: MORE:Hiroshima: of Alan Partridge: Enfield and Chums: to BBC Studios, bringing you the best of British TV! Here you'll find classic comedy, gripping drama, as well as the best documentaries, science and history! Take a look at complete listings for all our shows - we've got plenty to keep you entertained!Is there a BBC clip you'd love to see? Make sure you let us know by leaving a comment. Want to share your views with the team and win prizes? Join our fan panel: is a channel from BBC Studios who help fund new BBC programmes.Service information and feedback:
My life after the Air Force - MEInstagram collaborations or business inquiries email me at: Boesy31@gmail.com *********************************************I’m an Air Force Veteran who got out after 6 years of service as a Staff Sergeant E-5. I started making videos on this channel to document my journey in joining the United States Air Force. I went to MEPS on February 8, 2012. I left for Air Force BMT on January 8, 2013 and my date of separation from the Air Force is January 7, 2019. My videos represent my own opinion and do not reflect thoughts of the Air Force or DOD.
Amamos el humor mexicano! Cómo reaccionan dos alemanes al ver los mejores memes de México? Muchos de ustedes nos mandaron sus sugerencias por nuestras redes sociales (memes de ingenio mexicano, memes de la vida en México, videos virales mexicanos y mucho más!Espero que les guste este “Alemanes Reaccionando a Memes Mexicanos”No olvides de mandarnos tus mejores memes por el Twitter! Un abrazo #PinchesWeros😘 WeroWeroTV // WWTV▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬🔥Quieres unirte al equipo de los #PinchesWeros? Sé nuestro Co-Productor! 💋 También visítanos en nuestra Tienda en Linea: ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬🔥 Checa nuestros vídeos recomendados:• Alemanes Reaccionando a Telenovelas Mexicanas:• Alemanes Explorando Pueblo Mágico:Quieres ver más de WeroWeroTV? Checa las Playlists en la descripción abajo ▼✘ Extranjeros Probando Comida Mexicana: Vivir en Alemania: ✘ Vivir en México: ✘ Aprender Alemán Fácil: ✘ Extranjeros Reaccionan & Opinan: ✘ Hablando Español: ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬✌ Conéctate con nosotros:• Facebook: Twitter: Instagram de WeroWeroTV: Instagram de Jan: Instagram de Moe: • Instagram de Nils: Prueba nuestro Café 100% Mexicano de Oaxaca: ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬🎥 Nuestro Equipo:✘ Nuestro Laptop: Nuestra Computadora: Nuestro Celular I: Nuestro Celular II: Nuestro Micrófono para Celular: Nuestra Tarjeta de Memoria: Nuestro Tripié para Celular: Nuestra Camera: Nuestro Objetivo: Nuestro Tripié para Cámera: Nuestro Micrófono Externo: Nuestra Iluminación para vídeo: Nuestra Tienda de Fotografía: Nuestro Micrófono Externo I: Nuestro Micrófono Externo II: ✗ Enlaces de Afiliados: Para ti no se genera ningún costo extra. Sin embargo a nosotros nos pagan una pequeña parte de los ingresos. Los enlaces son del programa de afiliados de Amazon. ▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬▬🎵 Nuestra música de este vídeo:• Canal de WeroWeroMusic: Indie Fun Party 0:22 Ska Punk Fun 0:31 CatasKasger - Blueshift 4:59 NIVIRO - The Floor Is Lava 8:06 Elektronomia - Limitless Song: Catas & Kasger - Blueshift [NCS Release]Music provided by NoCopyrightSounds & WeroWeroMusic..Download: NIVIRO - The Floor Is LavaMusic provided by WeroWeroMusic.Video: Elektronomia - LimitlessMusic provided by WeroWeroMusic.Video:
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“Human Physiology” is a free online course on Janux that is open to anyone. Learn more at by the University of Oklahoma, Janux is an interactive learning community that gives learners direct connections to courses, education resources, faculty, and each other. Janux courses are freely available or may be taken for college credit by enrolled OU students.Dr. Heather R. Ketchum is an Associate Professor of Biology.Video produced by NextThought (© 2000-2014 The Board of Regents of the University of Oklahoma, All Rights Reserved.
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structure and functions - This immunology lecture explains about the chemical properties of interferons and the role of interferons in the immune response to fight against infections. (IFNs) are a bunch of signaling proteins made and launched through host cells in keeping with the presence of pathogens, comparable to viruses, micro organism, parasites, or tumor cells. This lecture will tell you the properties and functions of interferon in immune diffence. are also known as IFN. Please watch this video lecture throughly to know the details about the interferons.For more information, log on to-Shomu's Biology DVD set here-the study materials here-Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology-Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-storeShomu’s Biology assignment services – www.shomusbiology.com/assignment -helpJoin Online coaching for CSIR NET exam – www.shomusbiology.com/net-coachingWe are social. Find us on different sites here-Our Website – www.shomusbiology.comFacebook page- - www.slideshare.net/shomusbiologyGoogle plus- - you for watching the video lecture on interferons
Mas Risas y Risas con estas Recopilaciones de los Mejores Vídeos de Humor Mexicano que se Puedan Encontrar en las Redes Sociales, Espero los Disfruten.
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